Mariano-Aguilera et al. 2025

Contaminación por plaguicidas en miel y cera de abejas: implicaciones para la salud y la apicultura orgánica

Pesticide contamination in honey and beeswax: implications for health and organic beekeeping

Autor(es): Yamileth Yoshihey Mariano Aguilera, Neith Aracely Pacheco López, Ángel Humberto Cabrera Ramírez y Teresa del Rosario Ayora Talavera

Fuente: Mexican Journal of Technology and Engineering, Vol. 4, No. 3, pp. 14-21

DOI: https://doi.org/10.61767/mjte.004.3.1421

Resumen

La miel de Apis mellifera es un producto que se caracteriza por sus compuestos polifenólicos, como los ácidos fenólicos y flavonoides, para usos terapéuticos por su actividad antiinflamatoria, propiedades anticancerígenas, vitaminas C y E, enzimas, etc. La cera, otro producto de la colmena, se caracteriza por su estructura lipídica compleja, conformada por ésteres, hidrocarburos, ácidos grasos libres, etc., así como más de 300 compuestos bioactivos, y se emplea principalmente en el área cosmética y farmacológica. El uso indiscriminado de plaguicidas en la agricultura ha causado que residuos de estos contaminantes estén presentes en ellos. Estudios realizados en la Península de Yucatán han identificado plaguicidas que han impactado negativamente a los apicultores, ya que las abejas han sido afectadas, disminuyendo la producción, debilitando las colmenas y provocando su mortandad. Debido a esto, es importante realizar más investigaciones al respecto y mejorar las prácticas apícolas para el cuidado de las abejas y la calidad alimentaria, además de la concientización sobre el uso racional de plaguicidas; por lo que el objetivo de este artículo es analizar, visibilizar y exponer la problemática de la contaminación por residuos de plaguicidas en miel y cera de abejas de A. mellifera, su acumulación, los métodos de detección y los posibles efectos por la exposición.

Palabras clave: Apis mellifera, Yucatán, apicultura, residuos químicos, mortandad, contaminación alimentaria.

Abstract

Honey produced by the bee species Apis mellifera is characterized by its polyphenolic compounds, such as phenolic acids and flavonoids. These compounds are used for therapeutic purposes due to their anti-inflammatory activity and anticancer properties, as well as their vitamin C and E content and enzyme activity. Wax, another hive product, has a complex lipid structure consisting of esters, hydrocarbons, and free fatty acids, as well as over 300 bioactive compounds. It is primarily used in cosmetics and pharmacology. The indiscriminate use of pesticides in agriculture has resulted in residues of these contaminants being present in bees. Studies conducted on the Yucatán Peninsula have identified pesticides that have had a negative impact on beekeepers by affecting the bees, which has decreased production, weakened hives, and caused mortality. It is therefore important to conduct further research on this issue, improve beekeeping practices to ensure the health of bees and the quality of food, and raise awareness of the rational use of pesticides. The objective of this article is therefore to analyze and expose the problem of pesticide residue contamination in A. mellifera honey and beeswax, how it accumulates, how it is detected, and the possible effects of exposure.

Keywords: Apis mellifera, Yucatán, beekeeping, chemical residues, bee mortality, food contamination.

Referencias

Ashraf, S. A., Mahmood, D., Elkhalifa, A. E. O., Siddiqui, A. J., Khan, M. I., Ashfaq, F., Patel, M., Snoussi, M., Kieliszek, M., & Adnan, M. (2023). Exposure to pesticide residues in honey and its potential cancer risk assessment. Food and Chemical Toxicology, 180. https://doi.org/10.1016/j.fct.2023.114014

Brittain, C., & Potts, S. G. (2011). The potential impacts of insecticides on the life-history traits of bees and the consequences for pollination. Basic and Applied Ecology, 12(4), 321–331. https://doi.org/10.1016/J.BAAE.2010.12.004

Calatayud-Vernich, P., Calatayud, F., Simó, E., & Picó, Y. (2018). Pesticide residues in honey bees, pollen and beeswax: Assessing beehive exposure. Environmental Pollution, 241, 106–114. https://doi.org/10.1016/J.ENVPOL.2018.05.062

Codex Alimentarius Commission. (2022). CODEX NORMA PARA LA MIEL CODEX STAN 12-1981 www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCXS%2B12-1981%252FCXS_012s.pdf

Ek-Huchim, J. P., Rodríguez-Cab, E. M., López-Torres, E., Dzul-Caamal, R., Canepa-Pérez, I. M., & Osten, J. R. von. (2024). Pesticides and polycyclic aromatic hydrocarbons in honey and Apis mellifera from the Yucatán Peninsula, Mexico. Journal of Food Composition and Analysis, 132, 106293. https://doi.org/10.1016/J.JFCA.2024.106293

García, M. D. G., Duque, S. U., Fernández, A. B. L., Sosa, A., & Fernández-Alba, A. R. (2017). Multiresidue method for trace pesticide analysis in honeybee wax comb by GC-QqQ-MS. Talanta, 163, 54–64. https://doi.org/10.1016/J.TALANTA.2016.10.083

Gore, A., La Merrill, M., Patisaul, H., & Sargis, R. (2024). Endocrine Disrupting Chemicals: Threats to Human Health. Pesticides, Plastics, Forever Chemicals and Beyond. Endocrine Society. Hormone Science to Health.

Kasiotis, K. M., Zafeiraki, E., Manea-Karga, E., Anastasiadou, P., & Machera, K. (2023). Pesticide Residues and Metabolites in Greek Honey and Pollen: Bees and Human Health Risk Assessment. Foods (Basel, Switzerland), 12(4). https://doi.org/10.3390/FOODS12040706

Marti, J. N. G., Kilchenmann, V., & Kast, C. (2022). Evaluation of pesticide residues in commercial Swiss beeswax collected in 2019 using ultra-high performance liquid chromatographic analysis. Environmental Science and Pollution Research, 29(21), 32054–32064. https://doi.org/10.1007/S11356-021-18363-9/FIGURES/2

Mu, G., Yan, S., Pan, F., Xu, H., Jing, X., & Xue, X. (2025). Based on theoretical design simultaneous analysis of multiple neonicotinoid pesticides in beeswax by deep eutectic solvents extraction combined with UHPLC-MS/MS. Food Chemistry: X, 25, 102073. https://doi.org/10.1016/J.FOCHX.2024.102073

Mukherjee, I. (2009). Determination of pesticide residues in honey samples. Bulletin of Environmental Contamination and Toxicology, 83(6), 818–821. https://doi.org/10.1007/S00128-009-9772-Y

Mullin, C. A., Frazier, M., Frazier, J. L., Ashcraft, S., Simonds, R., vanEngelsdorp, D., & Pettis, J. S. (2010). High Levels of Miticides and Agrochemicals in North American Apiaries: Implications for Honey Bee Health. PLOS ONE, 5(3), e9754. https://doi.org/10.1371/JOURNAL.PONE.0009754

Oymen, B., Aşır, S., Türkmen, D., & Denizli, A. (2022). Determination of multi-pesticide residues in honey with a modified QuEChERS procedure followed by LC-MS/MS and GC-MS/MS. Journal of Apicultural Research, 61(4), 530–542. https://doi.org/10.1080/00218839.2021.2017540

Pacheco López, N. A., Cuevas Bernardino, J. C., & Vázquez Elorza, A. (2023). Estado actual del uso de pesticidas en productos agropecuarios de la península de Yucatán y su impacto en la sociedad: Retos y perspectivas (1st ed.).

Polanco Rodríguez, Á. G., Magaña Castro, T. V., Cetz Luit, J., & Quintal López, R. (2019, June). Uso de agroquímicos cancerígenos en la región agrícola de Yucatán, México. http://scielo.sld.cu/pdf/cag/v46n2/0253-5785-cag-46-02-72.pdf

Rodríguez Pérez, B., Canales Martínez, M. M., Penieres Carrillo, J. G., Cruz Sánchez, T. A., (2020). Composición química, propiedades antioxidantes y actividad antimicrobiana de propóleos mexicanos. Acta Universitaria, 30, 1–30. https://doi.org/10.15174/AU.2020.2435

Rodríguez-Aguilar, B., Peregrina-Lucano, A., Ceballos-Magaña, S., Rodríguez-García, A., Calderón, R., Palma, P., & Muñiz-Valencia, R. (2024). Spatiotemporal variability of pesticides concentration in honeybees (Apis mellifera) and their honey from western Mexico. Risk assessment for honey consumption. Science of the Total Environment, 947. https://doi.org/https://doi.org/10.1016/j.scitotenv.2024.174702

Rosales González, M., & Rubio Herrera, A. (1961). Estudios de cultura maya. Estudios de Cultura Maya, 35, 163–186. http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0185-25742010000100007&lng=es&nrm=iso&tlng=es

Stanojević, S. P., Milinčić, D. D., Smiljanić, N., Pešić, M. B., Nedić, N. M., Kolašinac, S., Dojčinović, B., Dajić-Stevanović, Z., & Kostić, A. (2024). Conventional vs. Organically Produced Honey—Are There Differences in Physicochemical, Nutritional and Sensory Characteristics? Foods, 13(22). https://doi.org/10.3390/foods13223573

Valdovinos-Flores, C., Alcantar-Rosales, V. M., Gaspar-Ramírez, O., Saldaña-Loza, L. M., & Dorantes-Ugalde, J. A. (2017). Agricultural pesticide residues in honey and wax combs from Southeastern, Central and Northeastern Mexico. Journal of Apicultural Research, 56(5), 667–679. https://doi.org/10.1080/00218839.2017.1340798

VanEngelsdorp, D., Evans, J. D., Saegerman, C., Mullin, C., Haubruge, E., Nguyen, B. K., Frazier, M., Frazier, J., Cox-Foster, D., Chen, Y., Underwood, R., Tarpy, D. R., & Pettis, J. S. (2009). Colony Collapse Disorder: A Descriptive Study. PLOS ONE, 4(8), e6481. https://doi.org/10.1371/JOURNAL.PONE.0006481

Végh, R., Csóka, M., Mednyánszky, Z., & Sipos, L. (2023). Pesticide residues in bee bread, propolis, beeswax and royal jelly – A review of the literature and dietary risk assessment. Food and Chemical Toxicology, 176. https://doi.org/10.1016/j.fct.2023.113806

Zohar, E., Cohen, H., Goldshlager, N., Barel, S., & Anker, Y. (2024). Detection of the amitraz pesticide in bee wax by hyperspectral imaging. Journal of Food Measurement and Characterization, 18(4), 3008–3017. https://doi.org/10.1007/S11694-024-02382-4/FIGURES/7